Haemophagocytic lymphohistiocitosis - a case report in infant
نویسنده
چکیده
Results We report a case of an infant, 1 year and 8 months old, male, that was in intensive care unit for five months with initial diagnosis of acute diarrhea, dehydration and hemolytic uremic syndrome. The infant developed fever, hepatosplenomegaly, cutaneous rash, bicytopenia, elevated serum ferritin, liver enzyme abnormalities, encephalitis, acute renal failure and serum hypogammaglobulinemia. The diagnosis of hemophagocytic lymphohistiocytosis was suspected and confirmed with biopsy of bone marrow with evidence of hemophagocytosis. Chemotherapy was instituted promptly with etoposide, dexamethasone and intravenous human immunoglobulin (immunomodulation dosis), with a favorable evolution and discharge from the intensive care unit.
منابع مشابه
Haemophagocytic lymphohistiocytosis in a Ghanaian child.
We report a case of a previously well nine-month-old infant who presented with prolonged fever, hepatosplenomegaly and pancytopenia. A diagnosis of haemophagocytic lymphohistiocytosis (HLH) was made during the course of hospital admission. There was good initial response to dexamethasone but the patient died less than two months after diagnosis. This is the first report of HLH from Ghana. The d...
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